js代码（myjs.js）：

/** @Title: This is a  file for ……* @Author: JackieZheng* @Date: 2022-04-12 09:24:13* @LastEditTime: 2022-04-12 09:40:55* @LastEditors: Please set LastEditors* @Description:* @FilePath: myjs.js*/function hello(name, word) {console.log(word, name)
}
let para_name = process.argv[2] ?? 'Jackie'
let para_word = process.argv[3] ?? 'Hello'
hello(para_name, para_word)

python代码：

"""
Title: python run js
Author: JackieZheng
Date: 2022-04-12 9:08:50
LastEditTime: 2022-04-12 09:38:12
LastEditors: Please set LastEditors
Description:
FilePath: runjs.py
"""
# -*- coding: utf-8 -*-
import os# 执行node 运行myjs.js文件 后边依次是要传递的参数 2，3，4……
command = os.popen("node myjs 杰克老师 您好")
# print(command.read()) 防止乱码建议用下边的方式
result = command.buffer.read().decode("utf-8")
command.close()
print(result)

运行结果：

E:\mini code\ (master -> origin) (cryptojs@1.0.0) 
λ python -u "e:\mini code\runjs.py"
您好 杰克老师