思路是这样的，数组集合装表头的信息，遍历这个集合，遍历过程中处理一下数据，然后就把每表头信息添加到dataGrid2.Columns.Add(templateColumn);

1，页面Xaml代码：

  <DataGrid x:Name="dataGrid" ItemsSource="{Binding DataSource}" AutoGenerateColumns="False" ColumnHeaderHeight="30" RowHeight="30"/>

2，声明一个类：

public class TY_DataGridColumsHeader
{public string Name { get; set; }public object HeaderTitle { get; set; }public object IsVisible { get; set; }
}

3，声明表头数据集合，再遍历。 

#region 自己创建的DataGrid表头var dpDescriptor2 = System.ComponentModel.DependencyPropertyDescriptor.FromProperty(DataGrid.ItemsSourceProperty, typeof(DataGrid));ObservableCollection<TY_DataGridColumsHeader> listheadttile = new ObservableCollection<TY_DataGridColumsHeader>();listheadttile.Add(new TY_DataGridColumsHeader(){HeaderTitle = "名称",Name = "Name"});listheadttile.Add(new TY_DataGridColumsHeader(){HeaderTitle = "年龄",Name = "Age"});dpDescriptor2.AddValueChanged(dataGrid2, (s, e) => {dataGrid2.Columns.Clear();foreach (var item in listheadttile){var templateColumn = new DataGridTemplateColumn(){Header = item.HeaderTitle,CellTemplate = (DataTemplate)XamlReader.Parse(GetCellTemplateXaml2(item.Name))};dataGrid2.Columns.Add(templateColumn);}});#endregion

4，cell的模版 

public static string GetCellTemplateXaml2(string listheadttile){var templateStr = "<DataTemplate xmlns=\"http://schemas.microsoft.com/winfx/2006/xaml/presentation\" xmlns:x=\"http://schemas.microsoft.com/winfx/2006/xaml\">";//templateStr += "<Grid><Grid.ColumnDefinitions><ColumnDefinition Width=\"*\" /><ColumnDefinition Width=\"Auto\" /></Grid.ColumnDefinitions>";//templateStr += $"<UniformGrid Columns=\"{(hasFlag ? cellBindingList.Count - 1 : cellBindingList.Count)}\">";//cellBindingList.ForEach(a =>//{//    if (!hasFlag || a != cellBindingList.Last())//    {//        templateStr += "<TextBlock Margin=\"10 0 10 0\" Text=\"{Binding " + a + "}\" VerticalAlignment=\"Center\" HorizontalAlignment=\"Center\" />";//    }//});//templateStr += "</UniformGrid>";//if (hasFlag)//{//    templateStr += "<TextBlock Grid.Column=\"1\" Text=\"{Binding " + cellBindingList.Last() + "}\" Width=\"50\" TextAlignment=\"Center\" VerticalAlignment=\"Center\" HorizontalAlignment=\"Center\" />";//}templateStr += "<Grid>";templateStr += "<TextBlock Margin=\"10 0 10 0\" Text=\"{Binding " + listheadttile + "}\" VerticalAlignment=\"Center\" HorizontalAlignment=\"Center\" />";templateStr += "</Grid></DataTemplate>";return templateStr;}