progeny本身有自己的R包，可以提取通路基因集信息，团队把他嵌入另一个R包decoupleR中完成富集分析。decoupleR自己有详细的针对bulk和scRNAseq的教程

简单安装一下

devtools::install_github('saezlab/OmnipathR')
devtools::install_github("saezlab/progeny") 
BiocManager::install("saezlab/decoupleR")

Inside PROGENy, one can find gene signatures for 14 different pathways:

• Androgen: involved in the growth and development of the male reproductive organs.
• EGFR: regulates growth, survival, migration, apoptosis, proliferation, and differentiation in mammalian cells
• Estrogen: promotes the growth and development of the female reproductive organs.
• Hypoxia: promotes angiogenesis and metabolic reprogramming when O2 levels are low.
• <